Fat Loss

5-Amino-1MQ

Half-life: — Oral capsule or tablet, taken once daily with or without food.

Warnings. Research compound with no completed human trials; long-term safety is unknown.

Mechanism

Inhibits the NNMT enzyme, increasing NAD+ salvage-pathway availability and SIRT1 activity, which enhances cellular metabolism and reduces adipogenesis and fat-cell size.

Overview

5-Amino-1MQ is a small-molecule inhibitor of NNMT (nicotinamide N-methyltransferase), an enzyme overexpressed in fat tissue that slows metabolism. By inhibiting NNMT it boosts cellular NAD+ availability and metabolic rate, promoting fat loss - particularly visceral fat - while preserving lean mass. Unlike most peptides it is taken orally.

Protocols

Metabolic Enhancement Cycle

Official BEGINNER

Daily oral dosing for body recomposition.

Goal: Fat loss and metabolic rate

Step 1 10w

100 mg · 1×/day · Morning

50-150mg orally once daily for 8-12 weeks. Start at 50mg and titrate up.