Fat Loss

AOD-9604

Half-life: 1h Subcutaneous injection on an empty stomach; avoid eating for ~1 hour after dosing.

Warnings. Research compound. Failed to show sufficient efficacy for drug approval but retains a favorable safety profile.

Mechanism

Mimics the lipolytic action of the C-terminal region of hGH, stimulating lipolysis and inhibiting lipogenesis via beta-3 adrenergic receptor pathways, without raising IGF-1 or affecting insulin sensitivity.

Overview

AOD-9604 is a modified fragment of human growth hormone (hGH residues 177-191) that stimulates fat breakdown without affecting blood sugar or promoting growth. It was developed as an anti-obesity drug and retains the lipolytic activity of hGH without its diabetogenic effects. It is generally very well tolerated.

Protocols

Fasted Lipolysis Protocol

Official BEGINNER

Fasted dosing to maximize fat mobilization.

Goal: Fat loss

Step 1 12w

300 mcg · 2×/day · Morning fasted and/or before bed

250-300mcg 1-2x per day, always fasted (morning before cardio is ideal). Run for 12 weeks.

Stacks well with

Semaglutide

⚠ Both affect glucose metabolism - monitor blood sugar