Cognitive

Selank

Half-life: 1h Intranasal spray, typically 1-2 sprays per nostril per dose.

Warnings. Research compound outside Russia/CIS. Generally very well tolerated.

Mechanism

Tuftsin analog that modulates GABAergic transmission, elevates BDNF, influences monoamine (serotonin/dopamine) metabolism, and regulates IL-6 expression.

Overview

Selank is a synthetic analog of the immunomodulatory tetrapeptide tuftsin with pronounced anxiolytic and nootropic properties. It reduces anxiety without sedation, tolerance, or dependence, making it an alternative to benzodiazepines. Developed in Russia and administered intranasally.

Protocols

Anxiolytic Cycle

Official BEGINNER

Two-week intranasal cycle for anxiety reduction and calm focus.

Goal: Anxiety reduction and mood

Step 1 2w

450 mcg · 1×/day · Morning or early afternoon

300-600mcg per day intranasally for 14 days. Can be split into two doses if desired.