Longevity

SS-31

Half-life: 4h Subcutaneous injection once daily.

Warnings. Investigational drug; not approved. Injection-site reactions reported in trials.

Mechanism

Selectively binds cardiolipin to stabilize mitochondrial cristae architecture, improving electron transport chain efficiency and reducing reactive oxygen species production.

Overview

SS-31 (Elamipretide) is a mitochondria-targeted tetrapeptide that selectively binds cardiolipin in the inner mitochondrial membrane. It improves mitochondrial efficiency, reduces oxidative stress, and is being studied for heart failure, mitochondrial myopathies, and age-related functional decline.

Protocols

Mitochondrial Support Cycle

Official ADVANCED

Daily dosing for 30 days to support mitochondrial function.

Goal: Mitochondrial health and energy

Step 1 4.3w

4 mg · 1×/day · Morning

4mg once daily for 30 days.