CJC-1295 (no DAC)
Warnings. Research compound. May elevate fasting glucose; avoid in active malignancy.
Mechanism
GHRH(1-29) analog that binds GHRH receptors on pituitary somatotrophs, stimulating synthesis and pulsatile secretion of endogenous growth hormone.
Overview
CJC-1295 without DAC (also called Mod GRF 1-29) is a modified GHRH analog that stimulates pulsatile growth hormone release from the pituitary. Without the Drug Affinity Complex it has a short half-life, preserving natural GH pulsatility. It is most commonly stacked with Ipamorelin.
Protocols
Standard GHRH Pulse Protocol
Official
INTERMEDIATE
Pulsatile dosing with weekly breaks to avoid pituitary desensitization.
Goal: Recovery, body composition, sleep
Step 1 12w
100 mcg · 3×/day · Morning fasted, post-workout, and/or before bed
100mcg 1-3x/day. Start with a single pre-bed dose and increase as tolerated. 5 days on, 2 days off.